| A-01 Registration at the conference venue Tuesday 14:00-18:00 |
| A-02 Opening ceremony, welcome reception and dinner Tuesday 19:00-22:00 |
| B-01 Registration at the conference venue Wednesday 08:00-08:45 |
| B-02 Welcome and Introduction Wednesday 08:45-09:00 |
| B-03 Praveen Thokala Overview and implementation of multi criteria decision analysis (MCDA) for benefit-risk assessment Wednesday 09:00-09:30 |
| B-04 Andreas Kouroumalis European regulatory views on benefit-risk assessment methodologies - role of MCDA and other model-based approaches Wednesday 09:30-10:00 |
| B-05 Kevin Marsh Current practices and gaps in benefit-risk assessment: opportunities for combining MCDA with model-based approaches Wednesday 10:00-10:30 |
| B-06 Coffee break, poster and software session I: posters in Group I (with poster numbers starting with I-) are accompanied by their presenter Wednesday 10:30-12:00 |
| B-07 Neeraj Gupta Model-Informed Drug Development (MIDD) for ixazomib, an oral proteasome inhibitor Wednesday 12:00-12:20 |
| B-08 Nadia Terranova Simulation analysis of absolute lymphocytes counts (ALC) and relapse rate (RR) following cladribine (re-)treatment rules in subjects with relapsing-remitting multiple sclerosis (RRMS) Wednesday 12:20-12:40 |
| B-09 Announcement of ACoP8 Wednesday 12:40-12:45 |
| B-10 Lunch Wednesday 12:45-14:10 |
| B-11 Joe Standing Scaling pharmacodynamics in children: Lessons from immunology, infectious diseases and critical care Wednesday 14:10-14:50 |
| B-12 Nick Holford Scaling renal function in neonates and infants to describe the pharmacodynamics of antibiotic nephrotoxicity Wednesday 14:50-15:10 |
| B-13 Tea break, poster and software session II: posters in Group II (with poster numbers starting with II-) are accompanied by their presenter Wednesday 15:10-16:40 |
| B-14 Hanna Silber Baumann Using pharmacokinetic simulation to guide dose escalation decisions for targeted IL2v immunocytokines Wednesday 16:40-17:00 |
| B-15 Simon Buatois Modelling approaches in dose finding clinical trial: Simulation-based study comparing predictive performances of model averaging and model selection. Wednesday 17:00-17:20 |
| B-16 Yuri Kheifetz Model-based individual managing of thrombocytopenia during multi-cyclic chemotherapy Wednesday 17:20-17:40 |
| B-17 Jurgen Langenhorst High exposure to fludarabine in conditioning prior to allogeneic hematopoietic cell transplantation predicts impaired CD4 reconstitution and lower probability of survival Wednesday 17:40-18:00 |
| C-01 Elisa Borella Paediatric trial design optimization using prior knowledge in combination with modelling & simulations Thursday 08:30-08:55 |
| C-02 John Diep Host-Pathogen interactions: A mechanism-based disease progression model to describe the pathogenesis of Acinetobacter baumannii pneumonia Thursday 08:55-09:20 |
| C-03 Morris Muliaditan Model-based rationale for drug combinations in tuberculosis Thursday 09:20-09:45 |
| C-04 Presentation of Lewis Sheiner student session awards Thursday 09:45-09:50 |
| C-05 Coffee break, poster and software session III: posters in Group III (with poster numbers starting with III-) are accompanied by their presenter Thursday 09:50-11:20 |
| C-06 Robert Leary An overview of non-parametric estimation methods used in population analysis Thursday 11:20-12:00 |
| C-07 Mats Karlsson A comparison of performance between parametric and nonparametric estimation for nonlinear mixed-effects models Thursday 12:00-12:20 |
| C-08 Announcement for WCoP 2020 Thursday 12:20-12:25 |
| C-09 Lunch Thursday 12:25-13:40 |
| C-11 Kristin Karlsson Regulatory pharmacometrics in the EU in practice and the role of the Modelling and Simulation Working Group Thursday 13:45-14:15 |
| C-12 Anna Nordmark The new draft EMA Guidance on PBPK – The qualification of the intended use concept Thursday 14:15-14:45 |
| C-13 Tea break, poster and software session IV: posters in Group IV (with poster numbers starting with IV-) are accompanied by their presenter Thursday 14:45-16:15 |
| C-14 In memoriam Matt Hutmacher Thursday 16:15-16:20 |
| C-15 Wojciech Krzyzanski Correction of the likelihood function as an alternative for imputing missing covariates Thursday 16:20-16:40 |
| C-16 Henrik Bjugård Nyberg SADDLE_RESET: more robust parameter estimation with a check for local practical identifiability Thursday 16:40-17:00 |
| C-17 Dmitry Onishchenko Joint modeling of overall survival and tumor size dynamics in non-small cell lung cancer: Clinical trial simulations and validation of predictions at study and subject levels Thursday 17:00-17:20 |
| C-18 Eva Germovsek Handling frequent observations of composite scores: Application to PROs in COPD Thursday 17:20-17:40 |
| C-19 Social event |
| D-01 Markus Krauß Translational systems pharmacology for acquisition of knowledge and prediction of drug pharmacokinetics across patient populations Friday 09:00-09:20 |
| D-02 Robin Michelet PBPK modeling of propofol using the middle out approach Friday 09:20-09:40 |
| D-03 Miro Eigenmann Therapeutic antibody concentrations at the biophase Friday 09:40-10:00 |
| D-04 Alan Maloney The 6 biggest pharmacometrics modelling mistakes! Friday 10:00-10:25 |
| D-05 Preview of PAGE2018 Friday 10:25-10:30 |
| D-06 Coffee break Friday 10:30-11:15 |
| D-07 Richard Höglund Pharmacokinetic-pharmacodynamic modelling of artesunate in patients with drug resistant and sensitive malaria Friday 11:15-11:35 |
| D-08 Salvatore D'Agate Model-based screening of compounds for the treatment of Chagas disease, a neglected tropical disease. Friday 11:35-11:55 |
| D-09 Carolina Llanos-Paez Balancing efficacy and reduction in renal function to optimize initial gentamicin dosing in children with cancer Friday 11:55-12:15 |
| D-10 Closing remarks Friday 12:15-12:25 |
| D-11 Audience input for potential PAGE2018 topics Friday 12:25-12:40 |
